The cord blood banking industry has been around for over 30 years, focusing on acquiring units for use in hematopoietic stem cell transplant. Recent research indicates that cord blood can be a valuable source of naïve cells for cell therapy manufacturing. Cord blood banks are evolving their processes to accommodate the use of cord blood…
Cellular starting material is the most critical component in the allogeneic cell therapy manufacturing process. Ensuring material access while maintaining quality, consistency and regulatory compliance are necessary throughout every stage of clinical development through commercialization. During this webinar, you will learn about: Factors to ensure streamlined access to high-quality, consistent starting material for allogeneic therapies…
A client initiated a Phase I clinical trial for its allogeneic cell therapy. Several months in, limited success recruiting patients had led to an expensive lack of progress. The client engaged with the CIBMTR® Bioinformatics Consulting team through NMDP BioTherapies℠ to identify U.S. states and counties with the highest density of patients and donors with…
An NMDP BioTherapies℠ client was like many allogeneic cell and gene therapy developers. It was developing a therapy for a blood condition and needed to build an off-the-shelf bank of cryopreserved cell sources. The client needed to understand: HLA genotypes to cover most patients in the U.S. How many patients would be covered by cells…
Along with gaining insights into how to tap into the expertise of cord blood banks and access therapy-matched cord blood units (CBUs), you’ll get a better understanding of: Comprehensive benefits of cords as an allogeneic cell source for cellular therapy Characteristics and attributes of the existing CBU inventory Importance of managing logistics for delivery of…
Can donor-reported characteristics, like race and ethnicity, impact data quality for allogeneic cell therapies? That’s one of the questions our expert panelists will discuss during our upcoming webinar. You’ll walk away with a better understanding of: Efficiencies in donor selection to reduce uncertainties about HLA matching and improve allogeneic cell therapy outcomes HLA complexity in cell source selection …
In this webinar, we focus on the scalability of donor starting material to support the growth and commercialization of allogeneic therapies. Throughout this discussion, we answer these questions on scalability and consistency in the allogeneic supply chain: What are the major gaps currently in the industry? How can we gain a better understanding of what…
Navigating international differences in regulations for cellular starting material is complex. This is particularly true because the rapid advancement of the industry sometimes precedes regulatory guidance. When you’re procuring cellular starting material or distributing a cell or gene therapy product across international borders, you must consider the country or regional requirements at play and where…
Learn why cord blood may be an excellent starting material for your therapy Cord blood has been used to provide life-saving treatments to patients for decades, but its full potential has not yet been tapped. Learn about scalability considerations when using cord blood. During this hour long on-demand webinar, our panelists discuss: Why it’s essential…